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角膜接触镜护理液最重要的功能是对镜片进行清洁和消毒,以及潜在的提高镜片配戴的舒适度。泪液中含有大量的蛋白和脂质,这些物质经常沉积在镜片上。在镜片配戴之后通过清洁去除镜片的沉积物的量随着镜片材料和所使用的角膜接触镜护理液的不同而不同。这篇文章回顾了不同的角膜接触镜护理液对泪液和镜片自身的影响,同时还回顾了多功能护理液和过氧化氢护理液对镜片清洁和消毒的效能,阐述了护理液过敏反应和其他与角膜接触镜相关的非感染性的并发症。(Adv StudOphthalmol.2008;5(3):76-78 )。角膜接触镜配戴与很多并发症有关。大多数并发症是非感染性,严重程度较低。然而,感染性并发症可威胁视力,更加令人担忧。最严重的并发症是微生物性角膜炎。而微生物性角膜炎首要的危险因素就是配戴角膜接触镜。角膜接触镜相关的感染病原体最常见的是细菌和革兰氏阴性菌(例如假单胞菌或者沙雷氏菌)或者,在较小程度上,革兰氏阳性菌(例如:葡萄球菌)2-5,但也可能包含非细菌性微生物,如最近爆发的真菌(镰刀霉菌)和原生动物(棘阿米巴)性角膜炎。6-9
The most important functions of contact lens solution are to clean and disinfect the lens, and potentially to improve the lens wearing comfort. Tears contain a lot of protein and lipid, these substances often deposited on the lens. The amount of deposit that is removed by cleaning after the lens is worn will vary depending on the material of the lens and the contact lens care solution used. This article reviews the impact of different contact lens solutions on tear and lens properties, as well as the efficacy of multi-purpose care solutions and hydrogen peroxide solutions on lens cleaning and disinfection, as well as the anaphylaxis and other Non-infectious complications associated with contact lenses. (Adv Stud Ophthalmol. 2008; 5 (3): 76-78). Contact lens wear and many complications related. Most complications are non-infectious and less severe. However, infectious complications can threaten vision and are even more worrisome. The most serious complication is microbial keratitis. The primary risk factor for microbial keratitis is to wear contact lenses. The most common contact lens-related infectious agents are bacteria and Gram-negative bacteria (such as Pseudomonas or Serratia) or, to a lesser extent, Gram-positive bacteria (such as Staphylococcus) 2 -5, but may also include non-bacterial microorganisms, such as the recent outbreak of fungi (Fusarium) and protozoan (Acanthamoeba) keratitis. 6-9