论文部分内容阅读
目的分析浙江省及与艾滋病疫情相关的9个省(自治区)HIV-1流行毒株亚型特征间的关系,了解流动人口对HIV-1流行特征的影响。方法检索并分析浙江省及与浙江省艾滋病疫情相关的9个省(自治区)HIV-1疫情、流行毒株构成及变迁的文献,查找两者毒株亚型间的联系。结果流动人口在HIV疫情流行地区与低流行地区间的传播中起着“桥梁”作用。流动人口输出较多的中西部省份HIV疫情相对高发,不同省HIV流行毒株有差异。目前,浙江省HIV-1型流行毒株以CRF01_AE、CRF07_BC、CRF08_BC和B’亚型为主,4种亚型占97.78%。浙江省流行的亚型构成,与流动人口输出地的HIV流行亚型及其变迁有关。结论 HIV疫情高发省份的外来流动病例对浙江省HIV疫情的传播和流行会造成一定影响,需继续加强HIV毒株监测。
Objective To analyze the relationship between HIV-1 subtypes and HIV-1 subtypes in 9 provinces (autonomous regions) related to AIDS epidemic in Zhejiang Province and to understand the influence of floating population on HIV-1 epidemiological characteristics. Methods To search and analyze the HIV-1 epidemic situation, the composition and changes of HIV-1 strains in 9 provinces (autonomous regions) related to the AIDS epidemic in Zhejiang Province and Zhejiang Province, and to find out the relationship between the two subtypes. Results The floating population played a “bridge” role in the spread of HIV epidemic areas and low prevalence areas. HIV epidemics in the central and western provinces, where more migrant workers are exported, are relatively high, with differences in HIV-endemic strains in different provinces. At present, HIV-1 type strains in Zhejiang Province are mainly CRF01_AE, CRF07_BC, CRF08_BC and B ’subtypes, with 97.78% of the four subtypes. The prevalence of subtypes in Zhejiang Province is related to the HIV subtypes and their changes in the outflow of migrants. Conclusion The outbreaks of migratory HIV in HIV-infected provinces may have an impact on the spread and prevalence of HIV in Zhejiang Province. HIV strains surveillance should continue to be strengthened.