论文部分内容阅读
目的:探讨直肠癌术前18FDGPET/CT标准摄取值(SUV)及临床病理特征与预后的关系。方法:应用单因素和多因素分析方法,对进行根治性切除术前行18FDGPET/CT检查的44例直肠癌患者的PET/CTSUV值及临床病理特征与5年生存率的相关性进行研究。结果:44例直肠癌患者5年总生存率为61.3%。单因素分析显示,患者的年龄、肿瘤浸润深度、有无淋巴结转移、术前18FDGPET/CTSUV值及血清癌胚抗原是影响患者预后的主要因素。应用Cox比例危险回归模型分析显示,肿瘤的浸润深度、淋巴结转移和18FDGSUV值是影响直肠癌患者的独立预后因素。结论:18FDGSUV是影响直肠癌患者预后的重要指标之一,可为临床判断直肠癌患者预后提供有效工具。
Objective: To investigate the relationship between preoperative 18FDGPET / CT uptake (SUV), clinicopathologic features and prognosis in patients with rectal cancer. Methods: The univariate and multivariate analysis was used to investigate the correlation between PET / CTSUV values and clinicopathologic features and 5-year survival rate of 44 patients with rectal cancer who underwent radical resection before 18FDGPET / CT. Results: The 5-year overall survival rate of 44 patients with rectal cancer was 61.3%. Univariate analysis showed that age, tumor invasion depth, lymph node metastasis, preoperative 18FDGPET / CTSUV value and serum carcinoembryonic antigen were the main factors affecting the prognosis of patients. Cox proportional hazard regression model analysis showed that the depth of invasion, lymph node metastasis and 18FDGSUV value were independent prognostic factors in patients with rectal cancer. Conclusion: 18FDGSUV is one of the most important prognostic factors in patients with rectal cancer, which may provide an effective tool for clinical diagnosis of rectal cancer patients.