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目的评估淮安市人类免疫缺陷病毒(感染者)/艾滋病(患者)(HIV/AIDS)实施免费抗病毒治疗的效果。方法收集2005—2013年在淮安市接受抗病毒治疗的HIV/AIDS的资料,分析治疗前后不同时间的CD4+T淋巴细胞计数以及治疗后病毒抑制率。结果共214例HIV/AIDS接受抗病毒治疗,在治194例,死亡20例。治疗前CD4+T淋巴细胞平均值为(170.1±117.3)个/μl,治疗后3、6个月和1、2、3、4、5年与治疗前相比,CD4+T淋巴细胞计数均有增加(P<0.05)。治疗1年后,CD4+T淋巴细胞计数较基线平均增加146.7个/μl,病毒抑制率为81.48%。有94例更换过抗病毒治疗药物,换药原因主要为药物不良。结论淮安市HIV/AIDS抗病毒治疗效果较好,可以有效抑制病毒复制,重建免疫功能,提高患者生存质量。
Objective To evaluate the effect of free antiviral treatment on human immunodeficiency virus (HIV) / AIDS (patient) (Huaian). Methods The data of HIV / AIDS patients receiving antiviral therapy in Huai’an from 2005 to 2013 were collected. The counts of CD4 + T lymphocytes and the virus inhibition rates after treatment were analyzed before and after treatment. Results A total of 214 cases of HIV / AIDS were treated with antiviral therapy, with 194 cases treated and 20 cases died. Before treatment, the average of CD4 + T lymphocytes was (170.1 ± 117.3) / μl, at 3, 6 months and 1, 2, 3, 4 and 5 years after treatment, CD4 + T lymphocyte count There was an increase (P <0.05). After 1 year of treatment, CD4 + T lymphocyte count increased by an average of 146.7 cells / μl from the baseline and the virus inhibition rate was 81.48%. There are 94 cases of the replacement of antiviral drugs, drug change mainly due to poor drug. Conclusion The anti-virus treatment of HIV / AIDS in Huaian City is effective and can effectively inhibit virus replication, rebuild immune function and improve the quality of life of patients.