论文部分内容阅读
肿瘤细胞对多种结构不同、作用靶位不同的抗肿瘤药物的抗药性,往往使肿瘤患者的化疗彻底失败.为逆转肿瘤细胞抗药性,国外做了大量研究来寻找、合成逆转抗药性的药物.最近,我们应用从中草药中提取的生物碱汉防己甲素(Tet)和抗肿瘤药物阿霉素(ADM)合用,成功地逆转多药抗性株(CHO/ADM)对 ADM 的抗性(该抗性株由本室
Tumor cells against a variety of different structures, the role of different target anti-tumor drug resistance, chemotherapy patients often make the failure of cancer patients.In order to reverse the tumor cell resistance, a large number of foreign studies to find, synthesis of drug resistance reversal Recently, we successfully reversed the resistance of multidrug resistant strains (CHO / ADM) to ADM using the alkaloid tetrandrine (Tet) extracted from Chinese herbal medicine in combination with the antitumor drug Adriamycin (ADM) This resistant strain consists of this room