【摘 要】
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乙二酸四乙酸(EDTA)是驱铅效果最好的络合剂之一。含钙络合剂还可预防血钙减少症,但因其对金属的络合无特异性,除铅外,锌和锰等金属亦显著地排出体外而导致内源性锌损失及可
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乙二酸四乙酸(EDTA)是驱铅效果最好的络合剂之一。含钙络合剂还可预防血钙减少症,但因其对金属的络合无特异性,除铅外,锌和锰等金属亦显著地排出体外而导致内源性锌损失及可能产生一些锰的毒性影响,并引起某些需锌、锰金属的生理功能紊乱。络合剂的效力主要取决于它与金属所成络合物的稳定
Oxalic acid tetraacetic acid (EDTA) is one of the best complexing agents to drive lead. Calcium-containing complexing agents can also prevent hypercalcemia, but because of its non-specific complexation with metals, in addition to lead, zinc and manganese and other metals are also significantly excreted resulting in endogenous zinc loss and may produce some Manganese toxicity, and cause some physiological functions required zinc, manganese metal disorders. The effectiveness of the complexing agent depends mainly on the stability of the complex with the metal
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