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目的对56例子宫癌肉瘤患者的临床病理情况进行综合分析,同时探讨其潜在的临床意义。方法 56例子宫癌肉瘤患者,根据其具体情况选择最合适的治疗措施,对诊断的临床病理结果进行综合分析,观察患者预后的主要影响因素。结果根据不同子宫癌肉瘤的病理分期,观察患者3年生存率,结果Ⅰ期患者3年生存率为66.7%,Ⅱ期患者为56.3%,Ⅲ期患者为21.1%,Ⅳ期患者为0。不同病理分期患者3年生存率相比,差异具有统计学意义(P<0.05)。将不同治疗方法的预后进行比较,结果为单纯手术治疗患者3年生存率为27.8%,手术治疗辅以化疗患者为42.9%,手术治疗辅以放疗患者为55.6%,手术治疗辅以放化疗患者为75.0%。不同治疗方法 3年生存率不同,差异具有统计学意义(P<0.05)。结论病理检查是诊断子宫癌肉瘤的金标准,除临床病理分期与患者的预后息息相关外,预后还与肿瘤的恶性程度,是否发生远处转移,治疗的方式相关;提高子宫癌肉瘤的早期诊断,早期治疗,延长患者的生存期至关重要。
Objective To analyze the clinical and pathological features of 56 patients with uterine carcinosarcoma and to explore its potential clinical significance. Methods 56 cases of uterine sarcoma patients, according to their specific circumstances choose the most appropriate treatment measures, the clinical and pathological diagnosis of the results of a comprehensive analysis to observe the prognosis of patients with the main factors. Results According to the pathological staging of different uterine sarcomas, the 3-year survival rate was observed. The 3-year survival rate was 66.7% in stage Ⅰ, 56.3% in stage Ⅱ, 21.1% in stage Ⅲ, and 0 in stage Ⅳ. The difference of 3-year survival rates of patients with different pathological stages was statistically significant (P <0.05). The prognosis of different treatment methods were compared, the results were 3-year survival rate of patients treated with surgery alone was 27.8%, 42.9% were treated with chemotherapy in patients with surgery, surgery was supplemented with radiotherapy 55.6%, surgical treatment with radiotherapy and chemotherapy patients 75.0%. The 3-year survival rates of different treatment methods were different, the difference was statistically significant (P <0.05). Conclusions Pathological examination is the gold standard for the diagnosis of uterine carcinosarcoma. In addition to the clinicopathological stage and the prognosis of patients, the prognosis is also related to the malignancy of the uterus, whether there is distant metastasis and the way of treatment. To improve the early diagnosis of uterine carcinosarcoma, Early treatment, to extend the survival of patients is essential.