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目的:探讨布托菲诺或氟比洛芬酯超前镇痛对硬膜外镇痛产妇母乳喂养及新生儿神经行为的影响。方法:以本院妇产科2014年3月至2015年7月收治的300例足月妊娠拟行剖宫产的孕妇为观察对象,将患者随机分为3组,各100例。对照组、布托啡诺组(BF组)、氟比洛芬酯组(FP组),对比分析3组观察对象的母乳喂养率以及新生儿神经行为影响。结果:BF组和FP组观察对象产后初乳时间、视觉模拟评分(VAS)评分和新生儿神经和适应能力评分(NACS)评分结果比较,差异无统计学意义(P>0.05),但两组观察对象各项观察指标结果均明显优于对照组(P<0.05)。结论:两种药物均可用于术后镇痛且对硬膜外镇痛产妇母乳喂养及新生儿神经行为无不良影响。
Objective: To investigate the effect of epidural analgesia with butofenprofen or flurbiprofen axetil on breastfeeding and neonatal neurobehavior in epidural analgesia. Methods: A total of 300 pregnant women who underwent cesarean delivery during March to July 2015 in our hospital from March 2014 to July 2015 were randomly divided into 3 groups (n = 100). The control group, the butorphanol group (BF group) and the flurbiprofen ester group (FP group). The breastfeeding rate and neonatal neurobehavioral effects of the three groups were compared. Results: There was no significant difference in postpartum colostrum time, visual analogue scale (VAS) score and neonatal neurological and adaptive score (NACS) between BF group and FP group (P> 0.05) Observations of the observed indicators of the results were significantly better than the control group (P <0.05). Conclusion: Both drugs can be used for postoperative analgesia and have no adverse effect on breastfeeding and neonatal neurological behaviors of epidural analgesia.