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抑郁症是以显著而持续的情绪低落为主要临床特征的一种精神异质性综合征。它是世界范围十大高发病率和病死率疾病之一。抑郁症的诊断主要以临床症状为主。因此,在针对抑郁症的动物研究中,抑郁行为学检测指标在鉴定模型复制以及抗抑郁药物疗效方面起重要作用。此外,由于临床抑郁患者常伴有焦虑,以及双向情感障碍即患者有抑郁和焦虑的交替表现,因此,焦虑行为的检测也是抑郁动物
Depression is a psychiatric heterogeneity syndrome characterized by significant and persistent depression as the main clinical feature. It is one of the top 10 high morbidity and mortality rates in the world. Depression diagnosis mainly based on clinical symptoms. Therefore, in animal studies on depression, depressive behavior testing indicators play an important role in the identification of model replication and antidepressant efficacy. In addition, anxiety is often associated with depression in patients with clinical depression as well as with bipolar disorder, which indicates depression and anxiety. Therefore, anxiety is also detected in depressed animals