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目的 了解恶性肿瘤患者医院感染情况及其影响因素。方法 对７３ 例医院感染患者感染部位、分布、病原学、药敏等情况进行分析。结果 感染以中晚期患者为多，占８３ ．６ ％ ，内源性感染为４３ ．８ ％ ；感染部位以呼吸道为主，占５９ ％ ；引起医院感染的病原菌主要为条件致病菌，其中革兰氏阴性菌占６６ ％ ，真菌占８ ．５ ％ 。混合菌感染明显增加，且耐药菌株多。结论 基础病情重、免疫功能低下、放疗或化疗、长期使用广谱抗生素、侵袭性操作等是恶性肿瘤患者发生医院感染的主要因素。
Objective To understand the status of nosocomial infection and its influencing factors in patients with malignant tumors. Methods The infection site, distribution, etiology, and drug susceptibility of 73 patients with nosocomial infection were analyzed. Results There were more patients with middle to late stage infections, accounting for 83%. 6 %, endogenous infection is 43. 8 % ; The infection site was dominated by the respiratory tract, accounting for 59 % ; the pathogens causing nosocomial infection were mainly pathogenic bacteria, of which Gram negative bacteria accounted for 66 % , fungi accounted for 8 . 5 %. Mixed bacterial infections increased significantly, and there were more resistant strains. Conclusions The basic condition, low immune function, radiotherapy or chemotherapy, long-term use of broad-spectrum antibiotics, and invasive operation are the main factors of nosocomial infection in patients with malignant tumors.