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目的探讨妊高征患者血液流变学与胎儿脐动脉血流阻力指标的相关性和对围产儿结局的影响。方法用粘度仪检测妊高征孕妇全血比粘度高切（ＢＶＨ）、全血比粘度低切（ＢＶＬ）、全血还原比粘度、血浆粘度（ＰＶ）；用离心机检测红细胞压积（ＨＣＴ）；应用彩色多普勒检测胎儿脐动脉血流阻力指标，比较妊高征患者血液流变学各值与胎儿脐动脉血流阻力指标各值相关关系。结果妊高征患者血液流变学各值与胎儿脐动脉血流阻力指标各值呈正相关性；ＨＣＴ、ＢＶＨ、ＢＶＬ、ＰＶ对妊高征的发生、发展及严重程度及脐动脉血流阻力指标有重要影响，导致胎儿胎盘循环障碍，脐动脉血流阻力指标升高。围产儿结局不良发生率，中、重度妊高征高于轻度妊高征（Ｐ＜０．０１）。结论多项指标监测妊高征血液流变学及胎儿脐血流动力学，可提高预测妊高征发生、发展及严重程度和对围产儿预后影响的准确性。
Objective To investigate the correlation between hemorheology and fetal umbilical artery resistance index and the effect on perinatal outcome in patients with pregnancy induced hypertension. Methods BVH, BVL, whole blood viscosity and plasma viscosity (PV) were measured by viscometer. HCT (HCT) was detected by centrifuge ); Color Doppler detection of fetal umbilical artery blood flow resistance index to compare the value of hemorheology in patients with PIH fetal umbilical artery blood flow resistance index values. Results The values of hemorheology in PIH were positively correlated with the values of umbilical artery resistance index. The incidence, development and severity of PIH in HCT, BVH and BVL and the indexes of resistance to flow in umbilical artery Have a significant impact, leading to fetal placental circulation disorder, umbilical artery blood flow resistance index increased. The incidence of perinatal unacceptable outcomes, moderate and severe PIH were higher than those of mild PIH (P <0.01). Conclusion A number of indicators to monitor the hemorheology of pregnancy induced hypertension and fetal cord blood flow dynamics can improve the prediction of the occurrence, development and severity of PIH and the accuracy of prognosis.