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采用手术结合术中及术后使用噻替派连续治疗膀胱上皮性恶性肿瘤95例。15年追踪结果:3年存活率88.5%,5年存活率84.5%,10年存活率60.9%;单个肿瘤、Ⅰ、Ⅱ级和 B_1(T_1)期前病人比多个肿瘤、Ⅲ、Ⅳ级和 B_2(T_3)期后的病人组存活率高、复发率低。本组病例治疗的特点是在噻替派化疗辅助下,扩大了经膀胱电切、膀胱部分切除的适应证,降低了术后复发率和提高了生存率;尽可能少作膀胱全切除,避免终生佩带尿袋、粪袋等弊病。
Ninety-five consecutive patients with cystocarcinoma were treated by intraoperative and postoperative use of thiotepa. Fifteen years follow-up results showed that the three-year survival rate was 88.5%, the five-year survival rate was 84.5% and the ten-year survival rate was 60.9%. Single tumor, grade Ⅰ, Ⅱ and B_1 And B_2 (T_3) patients after the high survival rate, low recurrence rate. The treatment of this group of patients is characterized by the addition of thiotepa chemotherapy, expanded by the bladder resection indications, partial resection of the bladder to reduce the recurrence rate and improve survival; minimal resection of the bladder as possible to avoid Lifetime wearing urine bags, dung bags and other ills.