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美国外科学会1981年对美国614所医院在1980年度收治之皮肤黑色素瘤4,545例进行了分析.在4,545例中,81%有色素痣大小、高度及色泽变化史,15%病人诉痣表面分泌物,8%诉痣周围发痒.57%病人就诊时病变浅于1.5mm,30%≥1.5mm,10%有局部转移,3%已有远处转移.此病男女同样常见,但在男性中好发于躯干部,而在女性中以下肢最常见.黑色素瘤可发生于各年龄组,中位年龄50岁,50岁以上病人中多见深型或浸润型病变.仅1%发生在黑人中.45%病人曾根据Breslow病变厚度法分类(Breslow Ⅰ～Ⅳ级厚度分别为0～0.75mm,0.76～1.50mm,1.51～2.25mm,2.26～3.0mm及>3.0mm).结果39%病人属Ⅰ级(此级病人预后极佳,治愈率可达95%以上),37%病人为Ⅲ级以上,此时局部及远处转移可能均增加.90%病人曾根据Clark浸润深度法分类(Clark Ⅰ～Ⅳ级深度分别为原位黑色素瘤,侵润至乳头状真皮层,侵润至乳头状
The American College of Surgeons conducted an analysis of 4,545 cases of skin melanoma admitted to 614 hospitals in the United States in 1980. Among 4,545 cases, 81% had a history of changes in the size, height, and color of nevi, and 15% of patients complained of surface discharge. , 8% complaints around the itching. 57% of patients with lesions shallower than 1.5mm, 30% ≥ 1.5mm, 10% have local metastases, 3% have distant metastases. The disease is equally common in men and women, but in men Occur in the trunk, and the lower extremities in females are the most common. Melanoma can occur in all age groups, with a median age of 50 years, and more commonly seen in patients over the age of 50, with deep or infiltrative lesions. Only 1% occur in blacks. 45% of patients had been classified according to the Breslow lesion thickness method (Breslow I to IV thickness were 0 ~ 0.75mm, 0.76 ~ 1.50mm, 1.51 ~ 2.25mm, 2.26 ~ 3.0mm and> 3.0mm). Results 39% of patients It belongs to grade I (the patient has an excellent prognosis with a cure rate of 95% or more), 37% of patients have grade III or higher, and both local and distant metastases may increase. 90% of patients have been classified according to Clark’s infiltration depth method ( Clark I to IV depths are melanoma in situ, infiltrating into the papillary dermis and infiltrating into papillary