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目的 探讨颅内节细胞胶质瘤(ganglioglioma,GG)的MR特点并分析误诊原因.方法 回顾性分析13例经病理证实的颅内GG的临床、病理及影像学资料.结果 肿瘤均位于幕上,囊结节型2例,囊实性型4例,实性型7例.结节与实性成分与正常脑灰质相比,瘤结节或瘤体实性部分呈等或稍低信号,T2WI呈稍高或高信号,T2FLAIR病灶以稍高信号为主;囊性成分信号与脑脊液类似.4例合并轻度水肿.5例患者DWI示囊性部分均为低信号,实性部分呈等或稍高信号.3例接受1H-MRS检查,实性部分ROI主要代谢物NAA峰稍减低,Cho升高,Cho/NAA值升高、Cho/Cr值升高,NAA/Cr值减低.增强扫描瘤结节或实性部分可无强化、轻至重度均匀或不均匀强化.10例术前误诊,分别诊断为血管母细胞瘤(1例):胚胎发育不良性神经上皮瘤(DNT)(1例),间变性星形细胞瘤(2例),6例误诊为胶质瘤(6例).结论 GG的MR表现多样,与胚胎发育不良性神经上皮瘤、多形性黄色星形细胞瘤等影像表现相似,术前易误诊,充分认识其MR特点,有助于鉴别诊断,提高术前诊断率.“,”Objective To evaluate MR features of ganglioglioma (GG) and to analyze cause s of msdiagnosis. Methods The clinical, pathological and imaging findings of 13 pathologically confirmed GG were retrospectively analyzed. Results All the neo-plasms were supratentorial. There were two cases of cystic nodular type,four cases of cystic and solid type and seven cases of solid type. The tumor nodules or solid parts of the tumor showed isointense or slightly hypointensity relative to gray matter on T, WI, slightly hyperintense or hyperintense on T2WI, slightly hyperintense on T2FLAIR. The cystic component signal was similar to the cerebrospinal fluid. In 4 patients with mild edema,DWI showed that the cystic part was hypointense, while the solid part showed equal or slightly hyperintense. Proton magnetic resonance spectrum of three patients showed Cho/NAA and Cho/Cr increasing, and NAA/Cr decreasing. After contrast administration, tumor nodules or solid parts may not be enhanced, mild to severe homoge-neous or uneven strengthening. Ten cases were misdiagnosis,including hemangioblastoma (n=1),dysembryoplastic neuroepithelial tumor (n=1), anaplastic astrocytoma (n =2), and glioma (n=6). Conclusion The Mr findings of GG were varied and presented dysembryoplastic neuroepithelial tumor and pleomorphic xanthoastrocytoma or other tumors, and were easily misdiag-nosed before operation. Fulll recognition of its MR characteristics will help differential diagnosis and improve the preoperative diagnostic rate.