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趋化因子是一族以ＩＬ－８为代表的可在诱导下分泌的小分子前炎症细胞因子，根据其结构的不同分为ＣＸＣ和ＣＣ两个亚族，前者对嗜中性粒细胞，后者对单核巨噬细胞、淋巴细胞、嗜酸性粒细胞和嗜碱性粒细胞有相对特异的趋化和活化作用，在哮喘慢性非特异性炎症反应中的作用正日益引起人们的关注。探讨其作用机制对于研制新型有效的哮喘防治方案极为重要。
Chemokines, a family of small molecule proinflammatory cytokines that can be secreted under the guidance of IL-8, are classified into two subfamilies, CXC and CC, according to their structure. The former, on neutrophils, the latter Relatively specific chemotactic and activation effects on mononuclear macrophages, lymphocytes, eosinophils and basophils are gaining more and more attention in chronic nonspecific inflammatory reactions of asthma. To explore its mechanism of action for the development of new and effective asthma prevention and control programs is extremely important.