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目的:探讨以硬质肿块为表现的耳鼻咽喉小涎腺来源腺样囊性癌的临床特征,病理特点及预后。方法:回顾性分析9例以硬质肿块为表现的发生于耳鼻咽喉各部位的小涎腺来源腺样囊性癌患者的临床资料。结果:本组患者从出现症状到确诊时间平均为4.3年,随访6个月~15年;9例均复发,死亡5例,其中肺转移3例,骨转移1例,颅内扩散1例;存活4例。带瘤生存时间最长为6年3个月。结论:本组9例病理类型均为实心型小涎腺来源腺样囊性癌,均有以硬质肿块生长为主要表现的特点,应及早诊断,第1次行扩大手术,术后辅以放疗,其预后远较其他类型差。
Objective: To investigate the clinical features, pathological features and prognosis of adenoid cystic carcinoma of the ear and nose and throat small salivary glands with hard mass. Methods: The clinical data of 9 patients with small salivary adenoid cystic carcinoma in various parts of otolaryngology were retrospectively analyzed. Results: The mean time from symptom onset to diagnosis was 4.3 years and followed up for 6 months to 15 years. All 9 cases were relapsed and 5 died, including 3 cases of lung metastasis, 1 case of bone metastasis and 1 case of intracranial diffusion. Survival in 4 cases. Tumor survival time of up to 6 years and 3 months. Conclusion: The pathological types of 9 cases were all solid salivary gland adenoid cystic carcinoma. All of them were characterized by the growth of hard mass. They should be diagnosed as soon as possible. Radiotherapy, the prognosis is far worse than other types.