论文部分内容阅读
目的 :在冠状动脉支架术后静脉滴注硝酸酯 ,观察其对术后胸痛和微梗死的影响。方法 :以行经皮冠状动脉腔内成形术及支架置入术的心绞痛 (稳定型、不稳定型 )患者 5 6例为入选对象 ,术后随机分为硝酸酯组(A组 ,2 8例 )和非硝酸酯组 (B组 ,2 8例 )。比较两组临床一般特征、冠状动脉病变、置入支架数及术后两组胸痛和微梗死的发生率。结果 :两组在临床一般特征方面、冠状动脉病变、置入支架数差异无显著性意义 (P >0 .0 5 ) ,硝酸酯对术后胸痛的发生率无影响 (A组 2 5 .0 % ,B组 2 8.6 % ,P >0 .0 5 ) ,但可显著减少术后微梗死的发生率 (A组 3.6 % ,B组 2 5 .0 % ,P <0 .0 1)。结论 :选择性支架术后静脉滴注硝酸酯可安全、有效地减少因支架术后并发冠状动脉微栓塞、分支闭塞等引起的微梗死 ,而对术后胸痛的发生无明显影响。
OBJECTIVE: To observe the effect of nitrates after postoperative coronary stenting on postoperative chest pain and micro-infarction. Methods: Fifty-six patients with angina pectoris (stable type and unstable type) who underwent percutaneous transluminal coronary angioplasty and stenting were randomly divided into three groups: group A (n = 28) And non-nitrate group (group B, 28 cases). The clinical features, coronary artery lesions, the number of stents and the incidence of chest pain and micro-infarction in both groups were compared. Results: There was no significant difference between the two groups in the general clinical features, the number of coronary artery lesions and the number of stents inserted (P> 0.05), and no effect of nitrates on the incidence of postoperative chest pain (Group A: 25.0 %, B group 8.66%, P> 0.05), but can significantly reduce the incidence of postoperative micro-infarction (3.6% in group A, 25.0% in group B, P <0.01). CONCLUSION: Nitric acid ester can be safely and effectively reduced after selective stenting with micro-infarction caused by coronary micro-embolism and branch occlusion after stenting, but no significant effect on postoperative chest pain.