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我们采用放免分析法联合检测血清FT_3、FT_4、TT_3、TT_4、TGA、TMA、TSH、rT_3共八个项目。分别对甲亢、甲减、甲状腺炎及甲亢治疗共164例患者及正常健康人58例进行检测分析,着重观察比较FT_3、FT_4、TT_3、TT_4的浓度变化及临床价值,将其检测统计结果报道如下。 材料和方法 一、对象:正常对照组58例(男21人,女37人),均来自健康查体者,年龄11～61岁,平均32.86岁。甲状腺疾病各组共164例(男36人,女128人),均经门诊和住院临床确诊的病人,年龄10～69岁,平均34.7岁,其中甲亢组55例,甲减组47例,甲亢治疗组20例,甲状腺炎组42例。 二、方法:血清FT_3、FT_4试剂盒由中国科学院上海原子核研究所提供;血清TT_3、TT_4、rT_3试剂盒山北方免疫试剂研究所提供;血清TGA、TMA试剂盒由卫生部上海生物制品研究所提供;TSH试剂盒为天津九鼎医学生物工程公司提供。以上均按试剂盒说明书操作。测定仪器为国营二六二厂生产的FJ-2008P型微机γ计数仪。各组计算SD,并进行t检验。 结果 甲状腺疾病各组与正常对照组的血清FT_3、FT_4、TT_3、TT_4、TGA、TMA、TSH、rT_3测定统计结果见表1。 甲亢组、甲减组血清FT_3、FT_4、TT_3、TT_4诊断闭性率统计结果见表2。
We used radioimmunoassay to detect serum total of eight items of FT_3, FT_4, TT_3, TT_4, TGA, TMA, TSH and rT_3. A total of 164 cases of hyperthyroidism, hypothyroidism, thyroiditis and hyperthyroidism were treated and 58 cases of normal healthy people were detected and analyzed, focusing on the observed changes in the concentration and clinical value of FT_3, FT_4, TT_3, TT_4, the test results reported as follows . Materials and Methods First, the object: normal control group of 58 patients (21 males and 37 females), all from the physical examination, aged 11 to 61 years, mean 32.86 years. Thyroid disease in each group a total of 164 cases (36 males and 128 females), were outpatient and inpatient clinically diagnosed patients, aged 10 to 69 years, mean 34.7 years, of which 55 cases of hyperthyroidism, hypothyroidism in 47 cases, hyperthyroidism 20 cases in the treatment group and 42 cases in the thyroiditis group. Methods: The serum FT_3 and FT_4 kits were provided by Shanghai Institute of Nuclear Research, Chinese Academy of Sciences. Serum TT_3, TT_4 and rT_3 kit were provided by Northern Institute of Immunoassay. Serum TGA and TMA kit were provided by Shanghai Institute of Biological Products, Ministry of Health ; TSH kit for Tianjin Jiuding medical bio-engineering company. The above instructions are based on kit operation. The measuring instrument is FJ-2008P microcomputer γ counter produced by State-owned No.266 Factory. Each group calculated SD, and t test. Results Thyroid disease in each group and the control group serum FT_3, FT_4, TT_3, TT_4, TGA, TMA, TSH, rT_3 statistical results in Table 1. Hyperthyroidism group, hypothyroidism serum FT_3, FT_4, TT_3, TT_4 diagnostic closure rate of statistical results in Table 2.