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目的探讨子宫内膜癌复发的高危因素。方法对2007年1月-2011年1月收治的364例子宫内膜癌患者进行回顾性分析,依据复发标准分为复发组38例,未复发组326例,观察两组高危因素并进行比较。结果复发组与未复发组高危因素比较差异有统计学意义(P<0.05)。结论子宫内膜癌复发与临床期别、肌层浸润、组织学分级、盆腔及腹主动脉旁淋巴结转移和腹腔冲液中有癌细胞等密切相关。在针对子宫内膜癌患者首次治疗中有上述高危因素者,应高度重视,积极进行术后综合放化疗,密切随访观察,以能够及早发现术后复发。
Objective To investigate the risk factors of recurrent endometrial cancer. Methods From January 2007 to January 2011, 364 cases of endometrial cancer were retrospectively analyzed. According to the recurrence criteria, they were divided into 38 cases of recurrence group and 326 cases of non-recurrence group. The risk factors of the two groups were observed and compared. Results The risk factors of recurrence group and non-recurrence group were significantly different (P <0.05). Conclusion The recurrence of endometrial carcinoma is closely related to clinical stage, myometrial invasion, histological grade, pelvic and para-aortic lymph node metastasis and cancer cells in peritoneal fluid. In the first treatment of endometrial cancer patients with the above risk factors, should attach great importance to active postoperative chemoradiotherapy, close follow-up observation to be able to early detection of postoperative recurrence.