论文部分内容阅读
目的:比较苯磺酸氨氯地平和厄贝沙坦对老年高血压病患者血压及24小时动态血压变异性的影响。方法:研究140例年龄在60～75岁之间的患者随机分为A、B两组,每组各70例,A组予以服用苯磺酸氨氯地平片(5mg/d)、B组予以厄贝沙坦片(150mg/d),对两组病人进行服药前及服药4周后24小时动态血压检查,比较两种药物对血压及24小时动态血压变异性的影响。结果:①两种降压药物均能有效降低血压(P<0.05)。②在控制24小时血压变异性方面,苯磺酸氨氯地平优于厄贝沙坦(P<0.05)。结论:与厄贝沙坦相比,苯磺酸氨氯地平能更理想的控制血压变异性。
Objective: To compare the effects of amlodipine besilate and irbesartan on blood pressure and 24 h ambulatory blood pressure variability in elderly patients with essential hypertension. Methods: A total of 140 patients aged 60-75 years old were randomly divided into A and B groups, 70 in each. A group was treated with amlodipine besylate (5mg / d), B group Irbesartan tablets (150mg / d), two groups of patients before taking the medication and 4 weeks after taking ambulatory blood pressure 24 hours to compare the two drugs on blood pressure and 24-hour ambulatory blood pressure variability. Results: ① Both antihypertensive drugs can effectively reduce blood pressure (P <0.05). (2) Amlodipine besylate was better than irbesartan in controlling blood pressure variability at 24 hours (P <0.05). Conclusion: Amlodipine besylate is more effective in controlling BPV than irbesartan.