A concise synthetic approach to dihydrochalcone:First total syntheses of bipinnatone A and B

• 出 处: Chinese Chemical Letters
• 发表日期: 2011年10期
• 关键词: concise commercially steps starting benzyl attractive bromide originally ketone

The first total syntheses of bipinnatone A and B have been achieved starting from commercially available phloroglucinol,p-hydroxybenzaldehyde in ten steps.Key features of the syntheses include Aldol reaction,aryl-alkylation and InCl_3-NaBH_4 selective reduction.

The first total syntheses of bipinnatone A and B have been achieved starting from commercially available phloroglucinol, p-hydroxybenzaldehyde in ten steps. Key features of the syntheses include Aldol reaction, aryl-alkylation and InCl_3-NaBH_4 selective reduction.