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一氧化碳(CO)是工业生产中分布最广的一种有害气体,当含碳物质燃烧不完全时均可产生。CO经呼吸道进入血液循环,与血红蛋白结合形成碳氧血红蛋白(HbCO)。血液中HbCO的浓度可以反应CO接触和吸收的多少,因此测定血液中HbC0的含量对CO中毒的临床诊断和暴露水平的生物监测指标具有重要意义。为了解长期接触低浓度CO工人血中HbCO的改变情况,我们于1989年对石家庄市某厂接触CO的283名工人及非接触者血液中HbCO含量进行了测定,现报告如下。
Carbon monoxide (CO) is the most widely distributed hazardous gas in industrial production and can be produced when the carbonaceous material is not fully burned. CO enters the bloodstream through the respiratory tract and combines with hemoglobin to form carboxyhemoglobin (HbCO). The concentration of HbCO in blood can reflect the contact and absorption of CO. Therefore, it is of great importance to determine the content of HbC0 in blood for the biological monitoring of clinical diagnosis and exposure to CO poisoning. In order to understand the change of blood HbCO in long-term exposure to low-concentration CO workers, we measured the HbCO content in blood of 283 workers and non-contact persons who were exposed to CO in a factory in Shijiazhuang in 1989 and are reported as follows.