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目的:通过对造成疑难配型的原因分析,探讨有效解决疑定型及难配型的措施。方法:对本院2014年1月—2015年12月疑难配型的病例进行分析。结果:共检出疑难样本42例分别由以下原因造成:同种抗体22例(52.4%),冷自身抗体6例(14.3%),自身抗体+直抗阳性4例(9.5%),同种抗体+直抗阳性1例(2.4%),直抗阳性3例(7.1%),未知抗体3例(7.1%),ABO亚型1例(2.4%),抗原减弱2例(4.8%)。结论:不规则抗体是导致临床疑难配型的主要原因,在实际工作中对各种原因需加以甄别,根据不同的原因给患者选择合适的血液制品,才能保证临床输血安全。
Objective: To analyze the causes of difficult match-up and discuss the effective measures to solve the doubtful and difficult-to-match type. Methods: The hospital from January 2014 to December 2015 difficult to match the case analysis. Results: A total of 42 cases of difficult samples were detected in 22 cases (52.4%), 6 cases (14.3%) with cold autoantibodies, 4 cases (9.5%) with autoantibodies and direct anti-positive antibodies Antibody + direct anti-positive in 1 case (2.4%), direct anti-positive in 3 cases (7.1%), unknown antibody in 3 cases (7.1%), ABO subtype in 1 case (2.4%), antigen weakening in 2 cases (4.8%). Conclusion: Irregular antibody is the main reason leading to difficult clinical matching. In practice, various reasons need to be screened. According to different reasons, patients can choose appropriate blood products to ensure the safety of clinical transfusion.