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目的:了解无棣县围产儿出生缺陷发生情况、临床类型及其分布特征,为制订降低该地区出生缺陷发生的干预措施提供科学依据。方法:根据2003～2009年无棣县所有出生医院围产儿出生资料,对围产儿中出生缺陷儿进行回顾性统计分析。结果:2003～2009年无棣县出生31 693例围产儿,出生缺陷儿195例,缺陷发生率为61.53/万,不同年份发生率比较差异无统计学意义,趋势性检验有统计学意义。7年中发生率最高的出生缺陷前5位种类依次为总唇裂、先天性心脏病、先天性脑积水、肢体短缩、多指(趾)及并指(趾)。结论:近7年无棣县总出生缺陷的发生水平有逐年上升的趋势,应加大相应干预措施的力度,以降低缺陷儿的出生率,提高出生人口素质。
Objective: To understand the occurrence, clinical types and distribution of perinatal infant birth defects in Wudi County and to provide a scientific basis for making intervention measures to reduce birth defects in this area. Methods: According to the data of perinatal birth among all the birth hospitals in Wudi County from 2003 to 2009, retrospective statistical analysis was made on the birth defects in perinatals. Results: A total of 31 693 cases of perinatal infants and 195 cases of birth defects were born in Wudi County from 2003 to 2009. The incidence of defects was 61.53 / 10000. There was no significant difference in incidence between different years, and the trend test was statistically significant. The top 5 birth defects with the highest incidence in 7 years were total cleft lip, congenital heart disease, congenital hydrocephalus, limb shortening, multiple fingers and digits. Conclusion: The incidence of total birth defects in Wudi County has risen year by year in recent seven years. The efforts of corresponding interventions should be strengthened to reduce the birth defects and improve the quality of birth population.