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依据蜂巢草(Leucas aspera)抗炎镇痛的传统用法,对其抑制前列腺素和抗氧化活性进行检测,并以双重活性指导对其进行分离。 取蜂巢草(1.55kg)以甲醇室温提取2次,得到的甲醇粗提物(81.4g)对PGE1、PGE2诱导的豚鼠回肠收缩具有抑制活性,并对DPPH自由基具有清除活性。取部分甲醇粗提
Based on the traditional use of anti-inflammatory and analgesic effects of Leucas aspera, its inhibitory activity on prostaglandin and antioxidant activity was tested and separated by dual activity guidance. The extract of hive (1.55kg) was extracted twice with methanol at room temperature. The crude methanol extract (81.4g) had inhibitory activity against PGE1 and PGE2-induced ileal contraction in guinea pigs and DPPH free radical scavenging activity. Take part of the crude methanol