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目的探讨眼附属器淋巴组织增生性病变的增殖活性与组织学分型的关系.方法用银染色技术对眼部淋巴增生病34例(良性淋巴组织增生14例,不典型淋巴组织增生9例,恶性淋巴瘤11例)进行银染核仁组织区(AgNORS)定量观察。结果发现良性淋巴组织增生与后二者AgNORS颗粒数量间均有极显著性的差异(P<0.01,P<0.001),不典型淋巴组织增生与恶性淋巴瘤之间AgNORs颗粒数量相差不显著。结论二种技术对眼附属器淋巴组织增生性病变组织学分型有一定意义。
Objective To investigate the relationship between proliferative activity and histological classification of ocular adnexal lymphoid proliferative lesions. Methods AgNORS quantitative analysis of 34 cases of benign lymphoid hyperplasia (benign lymphoid hyperplasia in 14 cases, atypical lymphoid hyperplasia in 9 cases, malignant lymphoma in 11 cases) was performed by silver staining technique. The results showed that there was a significant difference in the number of AgNORS particles between benign lymphoid tissue and the latter two (P <0.01, P <0.001), and there was a significant difference in the number of AgNORs between atypical lymphoid hyperplasia and malignant lymphoma Not obvious. Conclusions The two techniques have certain significance for histological classification of ocular adnexal lymphoid hyperplastic lesions.