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采用生理盐水浸泡与肌肉埋植的方法分别研究了可降解纤维/磷酸钙复合骨水泥的体外力学性能、体内降解性能以及相组成、微结构随浸泡(或植入)时间的变化规律。浸泡结果表明:浸泡初期,纤维的加入一定程度上降低了复合骨水泥的抗压强度,但大大改善了其断裂韧性,而且抗弯强度略有增加;浸泡后期,复合骨水泥的抗压强度、抗弯强度、断裂功均明显下降。体内降解结果表明,随着植入时间延长,含纤维复合骨水泥的降解速率及其增加幅度均高于未掺纤维骨水泥。类生理环境下含纤维复合骨水泥力学性能、降解性能的变化与纤维的降解、材料微观结构的变化密切相关。
The mechanical properties, in vivo degradation performance, phase composition and microstructure of degradable fiber / calcium phosphate composite cements with immersion (or implantation) time were studied by saline immersion and muscle implantation. The results of soaking showed that the fiber addition reduced the compressive strength of the composite cements to a certain extent, but the fracture toughness was greatly improved and the flexural strength slightly increased. In the later immersion, the compressive strength, Flexural strength, fracture work were significantly decreased. The results of in vivo degradation showed that the degradation rate and increasing extent of fibrous composite bone cement were higher than those of non-fibrous fibrous bone cement as the implantation time prolonged. Mechanical properties of fiber-containing composite cements in the physiological environment, the degradation of degradation and fiber degradation, microstructure changes are closely related.