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限食使鼠类等动物寿命延长,可能与蛋白代谢发生改变有关。故本实验探讨了限制食物蛋白对老龄鼠蛋白代谢与生理功能的影响。 Fischer 344大鼠,自由进食,分三组:①成龄(月龄8个月)23％蛋白饲料组、②老龄(24～25个月)23％蛋白饲料组、③老龄12％蛋白饲料组。氮平衡将②③组动物单个置于代谢笼内,测定其饲料、尿、粪中的氮含量。结果②组摄入与排出氮均显著高于③组,摄入与排出氮的差值,②组为一34.6-t±44.6、③组为+22.4±34.4。可见老龄鼠呈负氮平衡,限食蛋白使之反转为正氮平衡.根据摄入氮与粪氮计算蛋白消化能力,②③组间无差异,分别为
Food restriction to rats and other animals to extend the life expectancy may be related to changes in protein metabolism. Therefore, this study explored the impact of food protein on metabolism and physiological function of aging mice. Fischer 344 rats were fed freely and divided into three groups: (1) 23% protein feed group (aged 8 months), 23% protein feed group (aged 24-25 months), 12% protein feed group . Nitrogen balance ② ② ③ animals were placed in a single metabolic cage, the determination of feed, urine, feces in the nitrogen content. Results (2) The intake and discharge of nitrogen in group were significantly higher than those in group ③, and the difference between intake and discharge of nitrogen was ② 34.6-t ± 44.6 in group ② and +22.4 ± 34.4 in group ③. Visible aging mice showed a negative nitrogen balance, limiting protein to reverse the positive nitrogen balance.According to intake of nitrogen and fecal nitrogen protein digestion ability, ② ③ no difference between groups were