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β阻滞剂是目前临床上常使用的药物之一,有少数患者服用首剂小剂量时发生严重反应,引起休克,甚至死亡。所谓“β阻滞剂首剂综合征”(中华心血管病杂志,1985;13∶198。中华内科杂志,1986;9∶569)。本院见到1例,是首次服心得安10毫克引起休克,经抢救成活。因这类病例正式报道尚少,特予报道。患者女,61岁,住院号193,突然心慌,胸闷,乏力及腹胀3小时于1986年1月16日入院。患者在1985年11月曾住我院内科,诊断为甲亢伴甲心病,左右心室增大,房颤,三级心功能及慢性支气管炎伴感染,阻塞性肺气肿。
Beta blockers are currently used clinically one of the drugs, a small number of patients taking the first dose of a small dose of serious reactions, causing shock and even death. The so-called “beta blocker first-dose syndrome” (Journal of Cardiovascular Diseases, 1985; 13: 1988. Chinese Journal of Internal Medicine, 1986; 9: 569). The hospital to see 1 case, is the first time convinced 10 mg shock, survived. Due to the formal coverage of such cases is still small, especially to be reported. Female patient, 61 years old, hospital number 193, sudden panic, chest tightness, fatigue and bloating 3 hours on January 16, 1986 admission. Patients in November 1985 had our hospital internal medicine, diagnosis of hyperthyroidism with heart disease, left and right ventricular enlargement, atrial fibrillation, tertiary heart function and chronic bronchitis with infection, obstructive pulmonary emphysema.