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目的探讨舟山地区人群幽门螺杆菌(Hp)感染的分布特征及年度变迁。方法采用免疫金标法对2010年-2014年共2 296例患者进行血清Hp检测。结果共检出401例Hp阳性,阳性率为17.47%,其中男性306例,阳性率为20.97%;女性104例,阳性率为12.43%,男性阳性率高于女性,差异具有统计学意义(χ~2=23.41,P<0.01)。2010年-2014年Hp阳性率分别为10.10%、12.54%、14.79%、19.75%、23.48%,其中2013年、2014年阳性率均高于其前一年,差异具有统计学意义(χ~2值分别为28.10、12.87,P<0.01)。2010年-2012年男性Hp阳性率均高于女性,差异具有统计学意义(χ~2值分别为9.27、16.77、21.96,P<0.01)。结论舟山地区人群Hp感染率低于国内平均水平,近年来应加强对30岁以上人群血清Hp阳性率的监控。
Objective To investigate the distribution and annual changes of Helicobacter pylori (Hp) infection in Zhoushan area. Methods Immunoglobulin method was used to detect serum Hp in 2 296 patients from 2010 to 2014. Results A total of 401 Hp positive cases were detected, with a positive rate of 17.47%, of which 306 cases were male, the positive rate was 20.97%; 104 cases were female, the positive rate was 12.43%, the positive rate was higher in males than in females, the difference was statistically significant (χ ~ 2 = 23.41, P <0.01). The positive rates of Hp between 2010 and 2014 were 10.10%, 12.54%, 14.79%, 19.75% and 23.48% respectively. The positive rates of Hp in 2013 and 2014 were higher than those of the previous year (χ ~ 2 Values were 28.10,12.87, P <0.01). The positive rates of Hp in male from 2010 to 2012 were all higher than those in female (χ ~ 2 = 9.27, 16.77, 21.96, P <0.01 respectively). Conclusion The prevalence of Hp infection in Zhoushan population is lower than the national average level. In recent years, the detection rate of Hp positive rate in people over 30 years old should be strengthened.