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Poly I:C是一种良好的人工合成干扰素诱导物,因较易大量生产,成本较低,仅干扰素的十分之一,因此受到临床的重视。PolyI:C除具有诱导干扰素产生外,尚有抗肿瘤及增强淋巴细胞的免疫功能、对核酸代谢有抑制作用。目前应用PolyI:C的抗病毒和增强细胞免疫功能的作用来治疗乙型肝炎。我院于1978年曾对19例慢性迁延性及慢性活动性肝炎住院病人进行治疗,取得一定效果。 19例中显效12例(63.2％),好转2例(10.5％),无效5例(26.3％),总有效率为
Poly I: C is a good synthetic interferon inducer, due to easier mass production, lower cost, only one-tenth of interferon, so it has been clinically valued. PolyI: C addition to inducing interferon production, there are anti-tumor and enhance immune function of lymphocytes, nucleic acid metabolism inhibition. Hepatitis B is currently treated with PolyI: C’s antiviral and cellular immune enhancements. In our hospital in 1978, 19 cases of chronic persistent and chronic active hepatitis inpatients were treated, and achieved some results. Of the 19 cases, 12 cases (63.2%) were markedly effective, 2 cases (10.5%) were improved, and 5 cases (26.3%) were ineffective. The total effective rate was