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目的分析子痫前期再发与初发患者的临床特点,为子痫前期再发与初发的预防和治疗提供依据。方法将2012年7月-2016年7月来深圳市龙岗区第五人民医院分娩并符合筛选标准的子痫前期孕产妇250例,随机分成子痫前期再发组、经产妇初发组和初产妇初发组,统计3组子痫前期孕产妇的分娩有关临床资料。结果子痫前期再发组的分娩周数和疾病诊断周数均明显小于后两组,差异有统计学意义(P<0.05);子痫前期再发组的孕产妇合并慢性高血压、糖尿病以及慢性肾病并发症的发生情况均明显高于其他两组的发生情况,差异有统计学意义(P<0.05)。结论合并妊娠期高血压、糖尿病、慢性肾病等慢性疾病以及体重指数增加是子痫前期再发的重要因素;子痫前期再发的分娩孕周和诊断孕周相对较小,适当延长妊娠周数,可减少围产儿死亡率和患病率。
Objective To analyze the clinical features of patients with recurrent and primary preeclampsia and provide evidence for the prevention and treatment of recurrent and initial episodes of preeclampsia. Methods From July 2012 to July 2016, 250 pregnant women of pre-eclampsia who delivered to the Fifth People’s Hospital of Longgang District of Shenzhen City and met the screening criteria were randomly divided into preeclampsia recurrence group, Initial maternal group, statistical group 3 pre-eclampsia maternal delivery of clinical information. Results The number of weeks of delivery and the number of weeks of diagnosis in the relapse group were significantly lower than those in the latter two groups (P <0.05). The pregnant women with recurrent preeclampsia complicated by chronic hypertension, diabetes and The incidence of complications of chronic kidney disease were significantly higher than the other two groups, the difference was statistically significant (P <0.05). Conclusions Chronic diseases such as hypertension, diabetes mellitus, chronic kidney disease and other chronic diseases and the increase of body mass index during pregnancy are the important factors for the recurrence of preeclampsia. The pregnancy gestational weeks and the gestational weeks of pregnancy with recurrence in preeclampsia are relatively small, and the number of gestational weeks , Can reduce perinatal mortality and morbidity.