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目的观察面罩无创双水平气道正压通气(BiPAP)在慢性阻塞性肺疾病(COPD)合并慢性呼吸衰竭急性加重的治疗效果。方法入选2006年4月至2008年2月广东省丰顺县人民医院内科病例45例,呼吸机治疗组23例,在常规治疗基础上加用BiPAP无创呼吸机治疗,对照组22例,采用常规治疗基础上加呼吸兴奋剂治疗。对两组患者心率、呼吸频率、血氧饱和度、自觉症状进行比较。结果呼吸机治疗组患者心率、呼吸频率、血氧饱和度、自觉症状的改善优于呼吸兴奋剂治疗组,差异有统计学意义(P<0.01)。结论无创双水平气道正压机械通气辅助治疗COPD合并慢性呼吸衰竭急性加重具有肯定的疗效、较呼吸兴奋剂有明显的优势,并便于基层医院开展。
Objective To observe the therapeutic effect of mask noninvasive bi-level positive airway pressure (BiPAP) on acute exacerbation of chronic obstructive pulmonary disease (COPD) combined with chronic respiratory failure. Methods Forty-five cases of internal medicine and 23 cases of ventilator-treated patients in Fengshun County People’s Hospital of Guangdong Province from April 2006 to February 2008 were treated with BiPAP noninvasive ventilator on the basis of routine treatment. The control group was treated with routine Based on the treatment of respiratory stimulant therapy. The two groups of patients heart rate, respiratory rate, oxygen saturation, subjective symptoms were compared. Results The improvement of heart rate, respiratory rate, oxygen saturation and subjective symptoms in ventilator - treated patients was better than that of respiratory stimulants (P <0.01). Conclusions Noninvasive bi-level positive airway pressure mechanical ventilation has positive effect on acute exacerbation of chronic obstructive pulmonary disease (COPD) and chronic respiratory failure, which has obvious advantages over respiratory stimulant and is convenient for primary hospital.