Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes

• 作 者: Marloes van Zwam Ruth Huizinga
• 出 处: 世界最新医学信息文摘（电子版）
• 发表日期: 2016年11期
• 关键词: NEUROINFLAMMATION Immune regulation Autoreactive Tcells Tolerance CHEMOKINES CYT

Drainage of central nervous system(CNS) antigens to the brain-draining cervical lymph nodes(CLN) is likely crucial in the initiation and control of autoimmune responses during multiple sclerosis(MS). We demonstrate neuronal antigens within CLN of MS patie