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[目的]评价淋巴结转移率指标预测乳腺癌患者预后的意义。[方法]回顾性分析2004年1月至2010年12月期间149例淋巴结转移乳腺癌患者的临床资料。随访时间为12～60个月。数据分析采用SPSS16.0软件,生存曲线采用Kaplan-Meier法,并采用Log-rank检验。[结果]149例患者手术中检出淋巴结数共计3230枚,平均21.68±6.54枚。经病理学检查证实每例患者转移淋巴结数平均4.50±5.39枚。总的淋巴结转移率为20.7%(670/3230)。以淋巴结转移率(LNR)=0.25为界,LNR<0.25患者的3年生存率为95.7%,而LNR≥0.25患者的3年生存率为87.2%,两组差异有统计学意义(χ2=4.441,P=0.035)。[结论]LNR能较准确预测淋巴结转移乳腺癌患者的预后。LNR可作为一种潜在的乳腺癌预后指标。
[Objective] To evaluate the value of lymph node metastasis index in predicting the prognosis of patients with breast cancer. [Methods] The clinical data of 149 patients with lymph node metastatic breast cancer from January 2004 to December 2010 were retrospectively analyzed. Follow-up time was 12 to 60 months. Data analysis using SPSS16.0 software, survival curves using Kaplan-Meier method, and the use of Log-rank test. [Results] The number of lymph nodes detected in 149 cases was 3230 with an average of 21.68 ± 6.54. Pathological examination confirmed that each patient’s lymph node metastasis average 4.50 ± 5.39 pieces. The total lymph node metastasis rate was 20.7% (670/3230). The 3-year survival rate was 95.7% for patients with LNR <0.25 and 87.2% for patients with LNR ≥0.25, with a significant difference between the two groups (χ2 = 4.441 , P = 0.035). [Conclusion] LNR can accurately predict the prognosis of patients with lymph node metastasis of breast cancer. LNR can be used as a potential prognostic indicator of breast cancer.