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利用缺锌大鼠模型，研究缺锌对睾丸功能的影响，并观察不同剂量硫酸锌的治疗价值。结果：缺锌组大鼠血浆及器官锌含量显著降低，体重、血浆蛋白含量、精子计数、血浆及睾丸酮水平、睾丸ＲＮＡ和蛋白质含量等均显著低于自由摄食组和对饲组。给予缺锌大鼠补充硫酸锌４周，剂量为０．１５ｍｇ／ｋｇ时睾丸功能未见恢复，３．７５ｍｇ／ｋｇ时显示一定疗效，７．５０ｍｇ／ｋｇ则能有效提高缺锌大鼠锌储备和改善睾丸功能。提示缺锌损害睾丸功能，及时适量补锌则可使其恢复。
Zinc deficiency rat model was used to study the effect of zinc deficiency on testicular function and to observe the therapeutic value of different doses of zinc sulfate. Results: The levels of zinc and zinc in plasma and organs of rats in zinc deficiency group were significantly lower than those in free feed group and control group. Body weight, plasma protein content, sperm count, plasma and testosterone levels, testicular RNA and protein content were significantly lower than those in control group. Zinc deficiency rats were given zinc sulfate supplementation for 4 weeks, testosterone function was not restored when the dose was 0.15mg / kg, 3.75mg / kg showed a certain effect, 7.50mg / kg can effectively improve the zinc reserve of zinc-deficient rats And improve testicular function. Tip zinc deficiency damage testicular function, timely and appropriate zinc can make it recover.