论文部分内容阅读
目的：探讨内皮祖细胞在冠状动脉粥样硬化疾病中的治疗作用。方法：收集2013年4月～2014年8月我院诊断为冠心病心肌梗死的患者作为研究对象，定义为研究组；对照组为同期来我院未诊断为冠心病心肌梗死的患者。对比研究组和对照组内皮祖细胞水平。结果：研究组入院时、研究组出院时、对照组内皮祖细胞水平分别为：436.51±95.47p g/m l、278.6±69.4p g/m l、234.63±64.25pg/ml。对照组内皮祖细胞水平明显低于研究组入院时和出院时的水平，差异有统计学意义（P<0.05）。研究组出院时内皮祖细胞水平明显低于入院时水平，差异有统计学意义（P<0.05），即对照组内皮祖细胞水平最低，研究组入院时内皮祖细胞水平最高。结论：本次研究认为冠心病心肌梗死急性期患者内皮祖细胞表达明显增高，内皮祖细胞可能参与心肌梗死患者血管修复和再生过程。“,”Objective To investigate the therapeutic effect of endothelial progenitor cells in coronary atherosclerotic disease in. Methods From 2013 April~2014 year in August our hospital diagnosed as myocardial infarction coronary heart disease patients as the research object, defined as the study group;control group over the same period in our hospital was not diagnosed coronary heart disease in patients with myocardial infarction. Comparison between the study group and the control group, the level of endothelial progenitor cells. Results The study group on admission, at discharge, the level of the control group of endothelial progenitor cells were respectively:436.51±95.47pg/ml、278.6±69.4pg/ml、234.63±64.25pg/ml. The control level of endothelial progenitor cells group were significantly lower than those in the study group at the time of admission and discharge levels, the difference was statistically significant (P<0.05). Discharge progenitor cell level study group was significantly lower than at the time of admission levels, the difference was statistically significant (P<0.05), i.e., the control level of endothelial progenitor cells were the lowest, the study group during the admission of the highest level of endothelial progenitor cells. Conclusion This study found that acute phase of myocardial infarction in patients with coronary heart disease, endothelial progenitor cells expressed significantly increased, endothelial progenitor cells may be involved in vascular repair and regeneration process in patients with myocardial infarction.