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目的观察盐酸托莫西汀治疗注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)的临床效果。方法选择2010年8月—2012年4月收治的35例ADHD患儿,采用盐酸托莫西汀治疗60 d,比较治疗前后视听整合连续执行测试(integrated visual and auditory continuous performance test,IVA-CPT)结果,并观察药物不良反应。结果治疗60 d后,痊愈9例,好转20例,无效6例,总有效率82.86%,且在综合尺度控制商数、综合尺度注意商数、多动商数方面有明显改善。结论盐酸托莫西汀治疗ADHD效果良好,不良反应小,安全性好,但须及时处理出现的药物不良反应,提高用药的依从性。
Objective To observe the clinical effect of atomoxetine hydrochloride on attention deficit hyperactivity disorder (ADHD). Methods Thirty-five children with ADHD admitted to our hospital from August 2010 to April 2012 were treated with atomoxetine for 60 days. The results of integrated visual and auditory continuous performance test (IVA-CPT) Results, and observed adverse drug reactions. Results After 60 days of treatment, 9 cases recovered, 20 cases improved, 6 cases ineffective, and the total effective rate was 82.86%. There was a significant improvement in the quotient control of comprehensive scale, the attentional quotient of multiple scales and the number of hyperactivity quotient. Conclusion: Assessment of therapeutic efficacy of atomoxetine in the treatment of ADHD is good, the adverse reaction is small, and its safety is good. However, it is necessary to treat adverse drug reactions in time and improve the compliance of medication.