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目的:回顾尼日利亚东南部结膜上皮内瘤(CIN)的人口统计学及其它方面的特点。方法:回顾分析了1970/2000尼日利亚东南部一家中心实验机构有关CIN的组织病理学记录。结果:共有来自6所医院的12名医生报告了27例CIN组织病理记录,包括14例男性患者和13例女性患者。平均年龄为46.8岁,50～69岁组发病率最高。CIN多发生在颞侧或鼻侧缘,持续时间从1a以内(15例,55.6%)到10a(1例,3.7%)。仅有5例在CIN切除以后出现复发生长。结论:CIN主要见于黑人患者的水平缘部位,男女患者比例相当。眼科医生应对其尽早实施有效的治疗。
OBJECTIVE: To review the demographic and other aspects of conjunctival intraepithelial neoplasia (CIN) in southeastern Nigeria. METHODS: Histopathologic records of CIN in a central experimental facility in southeastern Nigeria 1970/2000 were retrospectively analyzed. RESULTS: A total of 12 physicians from 6 hospitals reported 27 CIN histopathological records, including 14 male patients and 13 female patients. The average age was 46.8 years old, the highest incidence of 50 to 69 years old group. CIN mostly occurred in the temporal or nasal margins, lasted less than 1a (15 cases, 55.6%) to 10a (1 case, 3.7%). Only 5 patients developed recurrence after CIN resection. Conclusion: CIN is mainly found in the horizontal edge of black patients, with a similar proportion of male and female patients. Ophthalmologists should treat them as soon as possible.