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为探讨两酮生物监测的最佳指标,选取醋酸纤维厂接触丙酮的男性工人110名为研究对象。平均年龄为37.6(18～56)岁,平均专业工龄为14.9(0.5～34.3)年,饮酒者占70.7%,吸烟者占74.7%于休息日后第1天工作班前收集血、尿、呼出气3种标本,8h工作班未留尿和收集呼出气。第2天班前再留尿和收集呼出气,班末最后一次采血,留尿和收集呼出气(后者均在班后5 min内完成)。如此,共采血样220份,留尿样及收集呼出气样本各440份。同时,工人配戴被动式个体采样器(呼吸带高度)以监测车间空气中丙酮浓度。上述各种样
In order to explore the best indicator of bioketone biosurfactant, 110 male workers exposed to acetone in cellulose acetate plant were selected as research objects. The average age was 37.6 (18-56 years). The average professional working age was 14.9 (0.5-34.3) years. The drinkers accounted for 70.7% and the smokers accounted for 74.7%. Blood, urine and exhaled breath were collected on the first day after work day 3 kinds of specimens, 8h working class did not stay urine and exhaled breath collection. On the second day, urine and air exhaled were collected before class, the last blood sample was taken at the end of the class, urinary retention and exhalation breath were collected (the latter were completed within 5 min after the shift). Thus, a total of 220 blood samples, leaving urine samples and collecting exhaled breath sample of 440 copies. At the same time, workers wear passive individual samplers (breathing zone height) to monitor the acetone concentration in the plant air. The above various samples