论文部分内容阅读
目的:观察益气养阴方联合西医疗法治疗原发性干燥综合征的临床疗效及对患者免疫指标的影响。方法:选取82例气阴两虚型原发性干燥综合征患者为研究对象,经随机数字表法分为观察组与对照组各41例,对照组行西医常规治疗,观察组在对照组治疗基础上加用益气养阴方治疗,2组患者均观察治疗3月。观察2组的治疗效果及免疫球蛋白G(IgG)、C4、红细胞沉降率(ESR)的变化。结果:观察组、对照组治疗总有效率分别为95.12%、80.49%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组IgG、C4、ESR均较治疗前改善(P<0.05,P<0.01),观察组IgG、ESR水平均低于对照组,C4水平高于对照组,差异均有统计学意义(P<0.05,P<0.01)。结论:采用益气养阴方联合西医疗法治疗气阴两虚型原发性干燥综合征患者,可促进症状改善,增强疗效,改善机体免疫力,具有较高的应用价值。
Objective: To observe the clinical curative effect of Yiqi Yangyin Recipe combined with Western medical therapy on primary Sjogren’s syndrome and its influence on immune index of patients. Methods: A total of 82 patients with primary deficiency syndrome of qi, yin and yin deficiency were selected as study subjects, divided into observation group and control group by random number table, 41 cases in each group. The control group received conventional treatment of western medicine group and the observation group in control group Based on the use of Yiqi Yangyin treatment, 2 patients were observed and treated for 3 months. The therapeutic effects and the changes of immunoglobulin G (IgG), C4, erythrocyte sedimentation rate (ESR) in the two groups were observed. Results: The total effective rates of the observation group and the control group were 95.12% and 80.49% respectively. There was significant difference between the two groups (P <0.05). After treatment, the IgG, C4 and ESR of two groups were improved compared with that before treatment (P <0.05, P <0.01). The levels of IgG and ESR in the observation group were lower than those in the control group, and the levels of C4 were higher than those in the control group (P <0.05, P <0.01). Conclusion: The treatment of qi and yin-deficiency syndrome patients with primary deficiency of qi and yin-deficiency syndrome by Qi-invigorating and nourishing Yin combined with Western medical therapy can promote the improvement of symptoms, enhance the curative effect and improve the immunity of the body, and has high application value.