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目的分析我院2011年药品不良反应发生情况,为临床合理用药提供参考。方法采用回顾性调查方法,应用Excel软件,对2011年收集到的326例ADR报告,分别按照患者的年龄和性别、给药途径、不良反应类型、药品种类、严重程度分级、ADR累及器官或系统及临床表现等方面进行分类统计分析。结果 326例ADR涉及97种药品,其中抗感染药物居首位(110例,33.74%);给药途径以静脉滴注为主(256例,78.53%);男女比例为1.08 1,男女比例接近。且60岁以上年龄段发生率最高(107例,32.82%);ADR临床表现以皮肤及其附件损害最常见(118例,36.20%)。结论应高度重视和加强ADR的监测,避免和减少不良反应的发生。
Objective To analyze the incidence of adverse drug reactions in our hospital in 2011 and provide a reference for clinical rational drug use. Methods A retrospective survey was conducted. Using Excel software, 326 ADR reports collected in 2011 were classified according to the patient’s age and sex, route of administration, type of adverse reactions, drug type and severity, ADR involving organs or systems And clinical manifestations and other aspects of statistical analysis. Results 326 cases of ADR involved 97 kinds of drugs, of which anti-infectives ranked first (110 cases, 33.74%); intravenous drip was the main route of administration (256 cases, 78.53%); the ratio of male to female was 1.08 1 . (107 cases, 32.82%) had the highest incidence in the age group of 60 years old. The clinical manifestations of ADR were the most common lesions (118 cases, 36.20%) with the skin and its appendages. Conclusion We should attach great importance to and strengthen the monitoring of ADR to avoid and reduce the incidence of adverse reactions.