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用硅铁冶炼粉尘对大白鼠进行肺脏致纤维化作用的实验研究。结果表朋，硅铁冶炼粉尘组全肺干重、湿重、胶原蛋白含量均明显高于空白对照组，但低于阳性对照石英粉尘组。动物染尘６个月双肺表面散在灰色粉尘灶，质地硬，轻度肺气肿。镜下肺间质增宽，Ｆｏｏｔ染色后多量网状纤维增生。染尘１２个月时，病理所见大量的网状纤维、胶原纤维增生、增多增粗，沿肺泡周围呈条索状。但病理改变稍轻于石英粉尘组。作者认为，硅铁冶炼粉尘对大白鼠肺脏有明显的致纤维化作用。
Experimental Study on Pulmonary Fibrosis Induced by Fe Ferrosilicon Smelting in Rats. Results Table friends, ferrosilicon smelting dust group lung dry weight, wet weight, collagen content were significantly higher than the blank control group, but lower than the positive control quartz dust group. Animal Dust 6 months Two lungs surface scattered in gray dust stove, texture hard, mild emphysema. Microscopic lung interstitial widened, Foot stained a large number of reticular fibrosis. Dyed dust 12 months, the pathology seen a large number of reticular fibers, collagen fibers hyperplasia, increased thickening, along the alveolar were cord-like. However, pathological changes slightly lighter than quartz dust group. The author believes that ferrosilicon smelting dust on the lungs of rats have obvious fibrosis.