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目的 早期评估新生儿败血症的预后。 方法 对80 例新生儿败血症的20 个变量进行非条件Logistic 单因素及多因素回归分析。 结果 单因素分析时9 个变量:白介素6(IL6) 、白介素8(IL8) 、一氧化氮( NO) 、黄疸、吃奶改变、哭声变化、入院体重、休克及器官功能衰竭与死亡有关;多因素分析剔除了上述变量中的NO、哭声变化、入院体重及休克4 个变量。 结论 IL6 、IL8 、吃奶改变、黄疸及器官功能衰竭可能是早期评估新生儿败血症预后的主要因素,这为临床治疗提供了理论依据
Objective To assess the prognosis of neonatal sepsis in the early stage. Methods Twenty variables in 80 neonates with sepsis were analyzed by univariate logistic regression and multivariate regression analysis. Results In the univariate analysis, nine variables: interleukin-6 (IL-6), interleukin-8 (IL-8), nitric oxide (NO), jaundice, changes in feeding, crying changes, admission weight, shock and organs Failure and death related; multivariate analysis excluded the above variables NO, crying changes, admission weight and shock four variables. Conclusion IL 6, IL 8, changes in feeding, jaundice and organ failure may be the early assessment of neonatal sepsis prognosis of the main factors that provide a theoretical basis for clinical treatment