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目的探讨认知行为干预对脑卒中后抑郁患者心理、认知功能及生活质量的改善效果。方法临床纳入我院2013年5月至2015年1月期间收治的脑卒中后抑郁患者106例,按随机数字表法进行分组,每组53例。对照组患者采用常规治疗,观察组在常规治疗基础上联合认知行为辅导。比较两组患者汉密尔顿抑郁量表(HAMD)、简明精神状态量表(MMSE)、洛文斯顿认知功能评定测验(LOTCA)以及日常生活能力评分(ADL)的差异。结果治疗前两组患者HAMD、MMSE、LOTCA各项评分及ADL评分均无差异(P>0.05);治疗后观察组HAMD、MMSE、LOTCA各项评分及ADL评分均优于对照组(P<0.05)。结论认知行为干预对脑卒中患者抑郁情绪、认知功能及生活质量改善效果明显,值得临床应用及推广。
Objective To explore the effect of cognitive behavioral intervention on the psychological, cognitive function and quality of life of patients with post-stroke depression. Methods 106 patients with post-stroke depression admitted to our hospital from May 2013 to January 2015 were randomly divided into three groups according to the random number table method, with 53 cases in each group. Patients in the control group were treated with conventional therapy. The observation group was given cognitive counseling based on routine treatment. The differences of HAMD, MMSE, LOTCA and ADL between the two groups were compared. Results There was no difference in the scores of HAMD, MMSE and LOTCA between the two groups before treatment (P> 0.05) and ADL scores (P> 0.05). After treatment, the score of HAMD, MMSE, LOTCA and ADL in observation group were better than those in control group ). Conclusion Cognitive and behavioral interventions have obvious effect on improving depression, cognitive function and quality of life in patients with stroke, which is worthy of clinical application and promotion.