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本文测定了４６例急性脑梗塞患者的血浆Ｄ－二聚体含量及抗凝血酶Ⅲ（ＡＴ－Ⅲ）、纤溶酶原（Ｐｇ）水平，并对其中１６例患者尿激酶溶栓后６ｈ的血浆Ｄ－二聚体再次检测。结果：脑梗塞患者组Ｄ－二聚体含量明显高于对照组（Ｐ＜０．０１），同时伴有ＡＴ－Ⅲ降低、Ｐｇ升高，溶栓前后结果经检验有显著性差异（Ｐ＜０．０５），表明急性脑梗塞患者存在血液高凝状态和继发纤溶激活。
In this study, we measured the levels of plasma D-dimer and the levels of AT-Ⅲ and Pg in 46 patients with acute cerebral infarction. Sixteen patients were treated with urokinase for 6h Of plasma D-dimer was tested again. Results: The content of D-dimer in patients with cerebral infarction was significantly higher than that in the control group (P <0.01), accompanied with the decrease of AT-Ⅲ and the increase of Pg. The results before and after thrombolysis were significantly different (P < 0.05), indicating that patients with acute cerebral infarction blood hypercoagulable state and secondary fibrinolytic activation.