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目的探讨中枢神经细胞瘤(CNC)诊断及治疗经验。方法回顾性分析16例CNC的诊断及显微手术治疗情况。采取纵裂-胼胝体-脑室入路5例,经皮质造瘘侧脑室入路9例,经枕下正中小脑蚓部入路1例,直接开颅切除1例。术后3例行放射治疗。结果术前误诊率62.5%。病理分级:WHOⅡ级7例,Ⅱ~Ⅲ级3例,Ⅲ级1例,未定级5例。病变全切除10例,次全切除4例,部分切除2例。除1例失访和1例复发外,其他病例恢复良好。结论 CNC多数位于脑室系统,在影像学上有其特点。选择适当的手术入路行显微手术治疗预后良好。
Objective To investigate the diagnosis and treatment of central neurocytoma (CNC). Methods A retrospective analysis of 16 cases of CNC diagnosis and microsurgical treatment. In 5 cases of longitudinal incision - corpus callosum - ventricles approach, 9 cases of transcortical fistula lateral ventricle approach, 1 case of suboccipitocerebellar vermis approach, 1 case of direct craniotomy. 3 cases after radiotherapy. Results The preoperative misdiagnosis rate was 62.5%. Pathological grade: WHO grade 7 cases, grade Ⅱ ~ Ⅲ 3 cases, grade Ⅲ in 1 case, not rated in 5 cases. Total lesion in 10 cases, subtotal resection in 4 cases, partial resection in 2 cases. In addition to one case of follow-up and one case of recurrence, other cases recovered well. Conclusion Most of the CNC is located in the ventricular system, which has its own characteristics in imaging. Select the appropriate surgical approach microsurgical treatment of good prognosis.