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在肾脏NO(一氧化氮)由内皮细胞和致密斑产生。它具有调节肾小球血流动态及肾小管功能的重要作用。NO的病态生理与某些肾脏疾病有关。NO由L-Arg(左旋精氨酸)在NOS(一氧化氮合成酶)的作用下生成。在肾脏,NOS除血管内皮细胞外,在致密斑有nNOS(...
NO (nitric oxide) in the kidneys is produced by endothelial cells and plaques. It has an important role in regulating glomerular blood flow dynamics and renal tubular function. The pathophysiology of NO is associated with certain kidney diseases. NO is produced by L-Arg (L-arginine) under the action of NOS (nitric oxide synthase). In the kidney, NOS in addition to vascular endothelial cells, in dense plaques nNOS (...