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为观察高温、噪声及复合因素对大鼠血浆及心肌血管紧张素Ⅱ（ＡⅡ）含量的影响，对７２只Ｗｉｓｔａｒ大鼠分别进行高温（４０℃，相对湿度８２％）、噪声（１１５ｄＢ）及高温与噪声复合暴露。用特异性放射免疫法进行检测。结果显示：（１）对照组、高温组、噪声组及复合组血浆ＡⅡ含量分别为３５８．７２±３５．７８、６２４．０８±３６．３２、７８３．２７±３４．３２及６１９．６５±３７．７２ｐｇ／ｍｌ，高温组、噪声组及复合因素组均明显高于对照组（Ｐ＜０．０１），其中噪声组升高更为明显，与高温组及复合组比较亦有显著性差异（Ｐ＜０．０５）；（２）对照组、高温组、噪声组及复合组心肌ＡⅡ分别为５９４．７８±８２．４６、９３５．１０±１５１．５１、３２６．２２±２８．４５及４３８．３７±５８．６３ｐｇ／ｍｇＷ．Ｗ，高温组明显升高，与对照组、噪声组及复合组比较均有显著性差异（Ｐ＜０．０１），噪声组明显下降，与对照组比较亦有显著性差异（Ｐ＜０．０５）。
To observe the effect of high temperature, noise and compound factors on the content of angiotensin Ⅱ (AⅡ) in plasma and myocardium of rats, 72 Wistar rats were subjected to high temperature (40 ℃, relative humidity 82%), noise (115dB) Compound exposure with noise. Specific radioimmunoassay was used. The results showed that: (1) The content of plasma AⅡ in control group, high temperature group, noise group and compound group were 358.72 ± 35.78, 624.08 ± 36.32, 783.27 ± 34.32 and 619.65 ± 37.72pg / ml, high temperature group, noise group and composite factor group were significantly higher than the control group (P <0.01), of which the noise group increased more significantly compared with the high temperature group and the composite group also had significant difference (P <0.05). (2) The myocardial AⅡ of control group, high temperature group, noise group and combination group were 594.78 ± 82.46, 935.10 ± 151.51, 326.22 ± 28.45 and 438.37 ± 58.63 pg / mgW. W, high temperature group was significantly higher, compared with the control group, noise group and composite group were significantly different (P <0.01), noise group decreased significantly compared with the control group also had significant difference (P <0. 05).