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P物质是一种脑肠肽,它广泛地分布在中枢神经系统和外周组织器官,在不同的部位发挥不同的生物学效应。在中枢它作为神经递质发挥作用且与痛觉传导有关,在外周神经它作为诱导神经源炎症的物质发挥作用。近年来发现P物质与胰腺的疾病如胰腺炎、糖尿病和胰腺癌关系密切。
Substance P is a ghrelin that is widely distributed in the central nervous system and peripheral tissues and organs and exerts different biological effects at different sites. In the center it functions as a neurotransmitter and is associated with pain conduction, which acts as a substance that induces neurogenic inflammation in the peripheral nerves. In recent years, substance P has been found to be closely related to pancreatic diseases such as pancreatitis, diabetes and pancreatic cancer.